Cancer can spread from where it started to another part of the body. The spread can occur by direct invasion, through blood or lymphatic. The original cancer is called the primary tumour. The cancer in another part of the body is called metastatic or secondary cancer. Metastatic cancer has the same type of cancer cells as the primary cancer.
For example, when breast cancer spreads to the lung, the cancer cells in the lungs are breast cancer cells. It is metastatic breast cancer, not lung cancer.
Researchers have identified 11 novel genes, whose inhibition can results in more than 99.5% block of spontaneous cancer spread in living cells. These genes are required for cancer cell motility and their expression in human is associated with metastatic risk. Study had used a shell less avian embryo to visualise the growth and spread of cancer cells in real time.
Now researchers have aimed to test the cancer spread associated genes and their product as drug target to mitigate cancer spread.
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